Information science and its interaction with other disciplines provide one of the most active engines for innovation in modern science and technology. To spearhead the interdisplinary research in this important field, under leadership of Prof. Andrew Yao, the Turing award Laureate, the Institute for Interdisciplinary information Sciences (IIIS) was created in 2011 at Tsinghua University. Now, we are at the 5th anniversary of the IIIS. To celebrate this event, we organize this symposium, inviting world leading experts from broad areas to talk about the recent exciting advances in the field of interdisplinary information sciences.